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- 01If you're interested in joining a study, you can browse open opportunities on our website and see if you qualify. If you're already part of the Patient Scientist Network (PSN), we'll also let you know when new studies that may be a good fit become available.If you're eligible, we'll mail everything you need to participate from home, including your collection kit, instructions, and prepaid return packaging. Depending on the study, you'll complete a few questionnaires and collect one or more small blood samples over time.
- 02ImYoo's mission is to build a new foundation for biomedical research samples and data, with patients at the center from the start.To achieve that, we are starting with building a platform which allows people to participate in immune studies that are most relevant to them. Our goal is to address the questions that are most pertinent to people's unique biologies and peculiarities. In the case of autoimmune diseases, it might be understanding what a sustainable remission looks like or which drugs work for some people and not others.During a study, we provide individuals with kits to self-collect painless capillary blood samples, and have the study participants send them back to ImYoo for processing and analysis.
- 03The Patient Scientist Network (PSN) is a community of people who want to help advance research.By joining the PSN, you'll be among the first to hear about new ImYoo studies that may match your health profile or interests. Joining the network doesn't commit you to participating in any study - you decide if and when you'd like to take part.
- 04Your immune system is constantly changing, but traditional research often captures only a few snapshots during clinic visits. By collecting small blood samples from home over time, ImYoo can better understand how immune-mediated diseases change throughout your everyday life - not just during appointments.
- 05ImYoo studies are observational. We never ask you to test a new treatment or change your medical care. Instead, we learn from your real-life health journey by combining at-home blood samples with information you choose to share about your symptoms, treatments, and experiences over time.In some cases, ImYoo may complement a clinical trial by collecting additional biological data between scheduled study visits.
- 06Many groups are underrepresented in clinical research, which can have negative consequences when they seek treatment. One major obstacle is that clinical trial sites are located too far from participants' homes. By allowing participants to self-collect their samples from home, ImYoo aims to include more patients who would otherwise be excluded from scientific research.
- 07Every ImYoo collection kit includes an FDA-cleared collection device, all the materials you'll need, a prepaid return label, and a step-by-step instruction guide. You can also watch our short overview video before getting started.Simply warm your arm, clean the collection site, place the device on your upper arm with the tube pointing downward, and press until you hear a click. The device will automatically collect a small blood sample (500 microliters) in up to 5 minutes. Once complete, cap the tube, invert until tube is fully painted, and mail your sample back using the original kit and the return label.If you have any questions, the ImYoo team is always here to help.
- 08Most people are surprised by how comfortable the collection is. More than 700 participants have successfully collected samples with ImYoo, and the vast majority report feeling little to no discomfort.The device uses a tiny microneedle that reaches only the surface of the skin. Gentle suction then draws a small blood sample into the collection tube, making the process feel very different from a traditional blood draw.While everyone's experience is different, most participants describe the collection as quick, easy, and more comfortable than they expected.
- 09Once your sample arrives at our laboratory, it is carefully processed by our scientific team.Depending on the study, researchers may analyze immune cells, proteins, genetic material, or other biological markers to better understand how the immune system changes over time. Samples may also be securely stored for future research.
- 10Some studies offer compensation for completed collections or study participation.Compensation varies by study and will always be explained before you enroll. You can chose to receive an Amazon gift card or donate it to charity.
- 11Yes. If you're part of the Patient Scientist Network (PSN) and participate in an ImYoo study, you'll have the option to receive a personalized immune report once the study is complete.Your report is designed to help you explore your research data and learn more about your immune profile. It is not a diagnostic test, medical evaluation, or substitute for advice from your healthcare provider. ImYoo conducts research, and any information shared is for research purposes only.
- 12Your privacy and safety are our top priorities. Every ImYoo study is reviewed by an Institutional Review Board (IRB) to help ensure your rights are protected.Your samples and health information are securely stored and de-identified before being used for research whenever possible, meaning your identity is not linked to the data being analyzed.Whenever permitted by the study, you'll also have the option to receive a personalized immune report based on your research data. These reports are for research purposes only and are not diagnostic or medical tests.
- 13Most of the standard blood tests that your doctor orders look at the proteins in your blood. Those tests can tell you what's wrong with you, but they don't always explain the underlying reason. For example, your antibody levels may be elevated, but what's the cause? More powerful tests attempt to answer this question by sequencing your DNA, but they also fall short. While they provide a high-level view of your genetic code, they don't fully explain how your DNA produces dysfunctional proteins. What bridges that gap between DNA and proteins? RNA, which changes in response to your environment, time-of-day, or diet. Some of these factors are in your control, which is why we believe single-cell RNA sequencing can get you actionable insights. We measure your RNA, because we recognize your body is always changing and we want to understand why.
- 14Traditional "bulk" RNA sequencing counts the number of RNA molecules produced by each gene in a sample. With single cell RNA sequencing it is possible to count the number of RNA molecules in individual cells in a sample, instead of summing all the cells together. Thus, "bulk" RNA sequencing is akin to a fruit smoothie, where you taste the combined flavors, but cannot discern its composition. Single-cell RNA sequencing reveals the recipe for each cellular smoothie— the exact number of berries, bananas, etc. We measure the RNA that is used to generate the protein produced by each immune cell, preserving its unique signal that would otherwise be lost in the "cell smoothie".
- 15Our current consent forms are linked below. As we prepare to enroll you into our studies, we send you these consent forms via survey link. You automatically receive an email copy of your consent form submissions.
- 16Absolutely. Many participants connect to share experiences, ask questions, and learn from each other's journeys. You can join the discord channel: https://discord.gg/aVu7epwnJ And find us in social media
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